Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032100-05
Application #
2066998
Study Section
Virology Study Section (VR)
Project Start
1992-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Genetics
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Liang, Chengyu; Rieder, Elizabeth; Hahm, Bumsuk et al. (2005) Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells. Virology 333:41-53
Mueller, Steffen; Wimmer, Eckard; Cello, Jeronimo (2005) Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event. Virus Res 111:175-93
Mueller, Steffen; Cao, Xuemei; Welker, Reinhold et al. (2002) Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis. J Biol Chem 277:7897-904
Pfister, Thomas; Feng, Huan; Wimmer, Eckard et al. (2002) Synchrotron radiation-induced X-ray emission to identify metal ions in preparations of purified protein. Biotechniques 32:134-6, 138, 140-1
Li, X; Lu, H H; Mueller, S et al. (2001) The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage. J Gen Virol 82:397-408
Pfister, T; Wimmer, E (2001) Polypeptide p41 of a Norwalk-like virus is a nucleic acid-independent nucleoside triphosphatase. J Virol 75:1611-9
Xiao, C; Bator, C M; Bowman, V D et al. (2001) Interaction of coxsackievirus A21 with its cellular receptor, ICAM-1. J Virol 75:2444-51
Pfister, T; Jones, K W; Wimmer, E (2000) A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. J Virol 74:334-43
Zhao, W D; Lahser, F C; Wimmer, E (2000) Genetic analysis of a poliovirus/hepatitis C virus (HCV) chimera: interaction between the poliovirus cloverleaf and a sequence in the HCV 5' nontranslated region results in a replication phenotype. J Virol 74:6223-6
Zhao, W D; Wimmer, E; Lahser, F C (1999) Poliovirus/Hepatitis C virus (internal ribosomal entry site-core) chimeric viruses: improved growth properties through modification of a proteolytic cleavage site and requirement for core RNA sequences but not for core-related polypeptides. J Virol 73:1546-54

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