Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032123-03
Application #
2067026
Study Section
Experimental Virology Study Section (EVR)
Project Start
1992-01-01
Project End
1997-01-31
Budget Start
1994-01-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Spear, Allyn; Ogram, Sushma A; Morasco, B Joan et al. (2015) Viral precursor protein P3 and its processed products perform discrete and essential functions in the poliovirus RNA replication complex. Virology 485:492-501
Ogram, Sushma A; Flanegan, James B (2011) Non-template functions of viral RNA in picornavirus replication. Curr Opin Virol 1:339-46
Spear, Allyn; Sharma, Nidhi; Flanegan, James Bert (2008) Protein-RNA tethering: the role of poly(C) binding protein 2 in poliovirus RNA replication. Virology 374:280-91
Silvestri, Lynn S; Parilla, Jessica M; Morasco, B Joan et al. (2006) Relationship between poliovirus negative-strand RNA synthesis and the length of the 3' poly(A) tail. Virology 345:509-19
Jurgens, Christy K; Barton, David J; Sharma, Nidhi et al. (2006) 2Apro is a multifunctional protein that regulates the stability, translation and replication of poliovirus RNA. Virology 345:346-57
Sharma, Nidhi; O'Donnell, Brian J; Flanegan, James B (2005) 3'-Terminal sequence in poliovirus negative-strand templates is the primary cis-acting element required for VPgpUpU-primed positive-strand initiation. J Virol 79:3565-77
Jurgens, Christy; Flanegan, James B (2003) Initiation of poliovirus negative-strand RNA synthesis requires precursor forms of p2 proteins. J Virol 77:1075-83
Morasco, B Joan; Sharma, Nidhi; Parilla, Jessica et al. (2003) Poliovirus cre(2C)-dependent synthesis of VPgpUpU is required for positive- but not negative-strand RNA synthesis. J Virol 77:5136-44
Barton, D J; O'Donnell, B J; Flanegan, J B (2001) 5' cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis. EMBO J 20:1439-48
Barton, D J; Morasco, B J; Flanegan, J B (1999) Translating ribosomes inhibit poliovirus negative-strand RNA synthesis. J Virol 73:10104-12

Showing the most recent 10 out of 14 publications