Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033600-04
Application #
2068665
Study Section
Experimental Immunology Study Section (EI)
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Fay, Marta M; Anderson, Paul J (2018) The Role of RNA in Biological Phase Separations. J Mol Biol 430:4685-4701
Fay, Marta M; Anderson, Paul J; Ivanov, Pavel (2017) ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells. Cell Rep 21:3573-3584
Lastres-Becker, Isabel; Nonis, David; Eich, Florian et al. (2016) Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation. Biochim Biophys Acta 1862:1558-69
Stoecklin, Georg; Kedersha, Nancy (2013) Relationship of GW/P-bodies with stress granules. Adv Exp Med Biol 768:197-211
Fujimura, Ken; Sasaki, Atsuo T; Anderson, Paul (2012) Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. Nucleic Acids Res 40:8099-110
Emara, Mohamed M; Fujimura, Ken; Sciaranghella, Daniele et al. (2012) Hydrogen peroxide induces stress granule formation independent of eIF2ýý phosphorylation. Biochem Biophys Res Commun 423:763-9
Ivanov, Pavel; Emara, Mohamed M; Villen, Judit et al. (2011) Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell 43:613-23
Simpson-Holley, M; Kedersha, N; Dower, K et al. (2011) Formation of antiviral cytoplasmic granules during orthopoxvirus infection. J Virol 85:1581-93
Emara, Mohamed M; Ivanov, Pavel; Hickman, Tyler et al. (2010) Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem 285:10959-68
Li, Chi Ho; Ohn, Takbum; Ivanov, Pavel et al. (2010) eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One 5:e9942

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