Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034000-04
Application #
2069063
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1993-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Lohsen, S; Majumder, P; Scharer, C D et al. (2014) Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types. Genes Immun 15:543-55
Zinzow-Kramer, W M; Long, A B; Youngblood, B A et al. (2012) CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments. Genes Immun 13:299-310
Majumder, Parimal; Boss, Jeremy M (2011) Cohesin regulates MHC class II genes through interactions with MHC class II insulators. J Immunol 187:4236-44
Choi, Nancy M; Majumder, Parimal; Boss, Jeremy M (2011) Regulation of major histocompatibility complex class II genes. Curr Opin Immunol 23:81-7
Yoon, Hyesuk; Boss, Jeremy M (2010) PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA. J Immunol 184:5018-28
Briggs, LaTese; Laird, Kholiswa; Boss, Jeremy M et al. (2009) Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP. Proteins 76:655-64
Reith, Walter; Boss, Jeremy M (2008) New dimensions of CIITA. Nat Immunol 9:713-4
Ting, Jenny P-Y; Lovering, Ruth C; Alnemri, Emad S et al. (2008) The NLR gene family: a standard nomenclature. Immunity 28:285-7
Niesen, Melissa I; Osborne, Aaron R; Yang, Hua et al. (2005) Activation of a methylated promoter mediated by a sequence-specific DNA-binding protein, RFX. J Biol Chem 280:38914-22