Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034361-04
Application #
2069493
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Szymczak, Wendy A; Deepe Jr, George S (2009) The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity. J Immunol 183:1964-74
Deepe Jr, George S; Gibbons, Reta S (2009) Interleukins 17 and 23 influence the host response to Histoplasma capsulatum. J Infect Dis 200:142-51
de Bastos Ascenco Soares, Renata; Gomez, Francisco J; de Almeida Soares, Celia Maria et al. (2008) Vaccination with heat shock protein 60 induces a protective immune response against experimental Paracoccidioides brasiliensis pulmonary infection. Infect Immun 76:4214-21
Deepe Jr, George S; Gibbons, Reta S (2008) TNF-alpha antagonism generates a population of antigen-specific CD4+CD25+ T cells that inhibit protective immunity in murine histoplasmosis. J Immunol 180:1088-97
Deepe, George S (2007) Tumor necrosis factor-alpha antagonism by the murine tumor necrosis factor-alpha receptor 2-Fc fusion protein exacerbates histoplasmosis in mice. J Interferon Cytokine Res 27:471-80
Cutler, Jim E; Deepe Jr, George S; Klein, Bruce S (2007) Advances in combating fungal diseases: vaccines on the threshold. Nat Rev Microbiol 5:13-28
Wuthrich, Marcel; Filutowicz, Hanna I; Allen, Holly L et al. (2007) V beta1+ J beta1.1+/V alpha2+ J alpha49+ CD4+ T cells mediate resistance against infection with Blastomyces dermatitidis. Infect Immun 75:193-200
Allen, Holly L; Deepe Jr, George S (2006) B cells and CD4-CD8- T cells are key regulators of the severity of reactivation histoplasmosis. J Immunol 177:1763-71
Scheckelhoff, Mark R; Deepe Jr, George S (2006) Pulmonary V beta 4+ T cells from Histoplasma capsulatum-infected mice respond to a homologue of Sec31 that confers a protective response. J Infect Dis 193:888-97
Deepe Jr, George S; McGuinness, Michael (2006) Interleukin-1 and host control of pulmonary histoplasmosis. J Infect Dis 194:855-64

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