Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034522-04
Application #
2069642
Study Section
Molecular Biology Study Section (MBY)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Moh, Akira; Zhang, Wenjun; Yu, Sidney et al. (2008) STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta. Diabetes 57:1227-35
Moh, Akira; Iwamoto, Yoshiki; Chai, Gui-Xuan et al. (2007) Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery. Lab Invest 87:1018-28
Zhang, Xuchen; Shan, Peiying; Jiang, Ge et al. (2006) Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injury. FASEB J 20:2156-8
Zhang, Xuchen; Shan, Peiying; Alam, Jawed et al. (2005) Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury. J Biol Chem 280:8714-21
Gao, Qian; Wolfgang, Michael J; Neschen, Susanne et al. (2004) Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. Proc Natl Acad Sci U S A 101:4661-6
Laouar, Yasmina; Welte, Thomas; Fu, Xin-Yuan et al. (2003) STAT3 is required for Flt3L-dependent dendritic cell differentiation. Immunity 19:903-12
Kano, Arihiro; Wolfgang, Michael J; Gao, Qian et al. (2003) Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. J Exp Med 198:1517-25
Jacoby, Jorg J; Kalinowski, April; Liu, Mu-Gen et al. (2003) Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. Proc Natl Acad Sci U S A 100:12929-34
Welte, Thomas; Zhang, Samuel S M; Wang, Tian et al. (2003) STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A 100:1879-84
Xie, B; Zhao, J; Kitagawa, M et al. (2001) Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion. J Biol Chem 276:19512-23

Showing the most recent 10 out of 18 publications