Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034937-02
Application #
2070224
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1995-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
O'Connor, Tamara J; Zheng, Huaixin; VanRheenen, Susan M et al. (2016) Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila. Infect Immun 84:2185-2197
Cianciotto, Nicholas P (2015) An update on iron acquisition by Legionella pneumophila: new pathways for siderophore uptake and ferric iron reduction. Future Microbiol 10:841-51
Aubi, Oscar; Flydal, Marte I; Zheng, Huaixin et al. (2015) Discovery of a Specific Inhibitor of Pyomelanin Synthesis in Legionella pneumophila. J Med Chem 58:8402-12
Portier, Emilie; Zheng, Huaixin; Sahr, Tobias et al. (2015) IroT/mavN, a new iron-regulated gene involved in Legionella pneumophila virulence against amoebae and macrophages. Environ Microbiol 17:1338-50
Burnside, Denise M; Wu, Yuyang; Shafaie, Saman et al. (2015) The Legionella pneumophila Siderophore Legiobactin Is a Polycarboxylate That Is Identical in Structure to Rhizoferrin. Infect Immun 83:3937-45
Gunderson, Felizza F; Cianciotto, Nicholas P (2013) The CRISPR-associated gene cas2 of Legionella pneumophila is required for intracellular infection of amoebae. MBio 4:e00074-13
Chatfield, Christa H; Cianciotto, Nicholas P (2013) Culturing, media, and handling of legionella. Methods Mol Biol 954:151-62
Zheng, Huaixin; Chatfield, Christa H; Liles, Mark R et al. (2013) Secreted pyomelanin of Legionella pneumophila promotes bacterial iron uptake and growth under iron-limiting conditions. Infect Immun 81:4182-91
Chatfield, Christa H; Mulhern, Brendan J; Viswanathan, V K et al. (2012) The major facilitator superfamily-type protein LbtC promotes the utilization of the legiobactin siderophore by Legionella pneumophila. Microbiology 158:721-35
Stewart, Catherine R; Muthye, Viraj; Cianciotto, Nicholas P (2012) Legionella pneumophila persists within biofilms formed by Klebsiella pneumoniae, Flavobacterium sp., and Pseudomonas fluorescens under dynamic flow conditions. PLoS One 7:e50560

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