Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI037139-01A2
Application #
2073768
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1996-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Colorado State University-Fort Collins
Department
Microbiology/Immun/Virology
Type
Schools of Arts and Sciences
DUNS #
112617480
City
Fort Collins
State
CO
Country
United States
Zip Code
80523
Safi, Hassan; Lingaraju, Subramanya; Amin, Anita et al. (2013) Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-?-D-arabinose biosynthetic and utilization pathway genes. Nat Genet 45:1190-7
Tatham, Elizabeth; Sundaram Chavadi, Sivagami; Mohandas, Poornima et al. (2012) Production of mycobacterial cell wall glycopeptidolipids requires a member of the MbtH-like protein family. BMC Microbiol 12:118
Torrelles, Jordi B; Sieling, Peter A; Zhang, Nannan et al. (2012) Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells. Glycobiology 22:1118-27
Somashekar, Bagganahalli S; Amin, Anita G; Tripathi, Pratima et al. (2012) Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis. J Proteome Res 11:4873-84
Zhang, Jian; Angala, Shiva K; Pramanik, Pradeep K et al. (2011) Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors. ACS Chem Biol 6:819-28
Somashekar, B S; Amin, Anita G; Rithner, Christopher D et al. (2011) Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies. J Proteome Res 10:4186-95
Zhang, Jian; Amin, Anita G; Holemann, Alexandra et al. (2010) Development of a plate-based scintillation proximity assay for the mycobacterial AftB enzyme involved in cell wall arabinan biosynthesis. Bioorg Med Chem 18:7121-31
Amin, Anita G; Angala, Shiva K; Chatterjee, Delphi et al. (2009) Rapid screening of inhibitors of Mycobacterium tuberculosis growth using tetrazolium salts. Methods Mol Biol 465:187-201
Maloney, Erin; Stankowska, Dorota; Zhang, Jian et al. (2009) The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides. PLoS Pathog 5:e1000534
Shi, Libin; Torrelles, Jordi B; Chatterjee, Delphi (2009) Lipoglycans of Mycobacterium tuberculosis: isolation, purification, and characterization. Methods Mol Biol 465:23-45

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