Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037277-05
Application #
2073965
Study Section
Special Emphasis Panel (ZRG5-BM-1 (05))
Project Start
1994-09-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Edmondson, Diane G; Prabhakaran, Sabitha; Norris, Steven J et al. (2017) Enhanced Protective Immunogenicity of Homodimeric Borrelia burgdorferi Outer Surface Protein C. Clin Vaccine Immunol 24:
Norris, Steven J (2014) vls Antigenic Variation Systems of Lyme Disease Borrelia: Eluding Host Immunity through both Random, Segmental Gene Conversion and Framework Heterogeneity. Microbiol Spectr 2:
Magnarelli, Louis A; Williams, Scott C; Norris, Steven J et al. (2013) Serum antibodies to Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti in recaptured white-footed mice. J Wildl Dis 49:294-302
Magnarelli, Louis A; Norris, Steven J; Fikrig, Erol (2012) Serum antibodies to whole-cell and recombinant antigens of Borrelia burgdorferi in cottontail rabbits. J Wildl Dis 48:12-20
Norris, Steven J (2012) How do lyme borrelia organisms cause disease? The quest for virulence determinants(). Open Neurol J 6:119-23
Norris, Steven J; Howell, Jerrilyn K; Odeh, Evelyn A et al. (2011) High-throughput plasmid content analysis of Borrelia burgdorferi B31 by using Luminex multiplex technology. Appl Environ Microbiol 77:1483-92
Coutte, Loïc; Botkin, Douglas J; Gao, Lihui et al. (2009) Detailed analysis of sequence changes occurring during vlsE antigenic variation in the mouse model of Borrelia burgdorferi infection. PLoS Pathog 5:e1000293
Lin, Tao; Gao, Lihui; Edmondson, Diane G et al. (2009) Central role of the Holliday junction helicase RuvAB in vlsE recombination and infectivity of Borrelia burgdorferi. PLoS Pathog 5:e1000679
Embers, Monica E; Liang, Fang Ting; Howell, Jerrilyn K et al. (2007) Antigenicity and recombination of VlsE, the antigenic variation protein of Borrelia burgdorferi, in rabbits, a host putatively resistant to long-term infection with this spirochete. FEMS Immunol Med Microbiol 50:421-9
Norris, Steven J (2006) Antigenic variation with a twist--the Borrelia story. Mol Microbiol 60:1319-22

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