Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI038532-02
Application #
2004346
Study Section
Special Emphasis Panel (SRC (55))
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Davis
Department
Pathology
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Brown, Amanda; Gartner, Suzanne; Kawano, Thomas et al. (2005) HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-tagged HIV-1 reporter virus. J Leukoc Biol 78:675-85
Brown, Amanda; Moghaddam, Shaghayegh; Kawano, Thomas et al. (2004) Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages. J Gen Virol 85:1463-9
Chakrabarti, Lisa A; Metzner, Karin J; Ivanovic, Tijana et al. (2003) A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication. J Virol 77:1245-56
Linnemann, Thomas; Zheng, Yong-Hui; Mandic, Robert et al. (2002) Interaction between Nef and phosphatidylinositol-3-kinase leads to activation of p21-activated kinase and increased production of HIV. Virology 294:246-55
Greene, Warner C; Peterlin, B Matija (2002) Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med 8:673-80
Geyer, Matthias; Yu, Haifeng; Mandic, Robert et al. (2002) Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery. J Biol Chem 277:28521-9
Fackler, O T; Peterlin, B M; Weis, K (2001) Lessons from HIV: movement of macromolecules inside the cell. Curr Mol Med 1:1-7
Fackler, O T; d'Aloja, P; Baur, A S et al. (2001) Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivity. J Virol 75:6601-8
Zheng, Y H; Plemenitas, A; Linnemann, T et al. (2001) Nef increases infectivity of HIV via lipid rafts. Curr Biol 11:875-9
Fackler, O T; Lu, X; Frost, J A et al. (2000) p21-activated kinase 1 plays a critical role in cellular activation by Nef. Mol Cell Biol 20:2619-27

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