Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039938-01
Application #
2076886
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Chou, Sunwen (2015) Approach to drug-resistant cytomegalovirus in transplant recipients. Curr Opin Infect Dis 28:293-9
Chou, Sunwen; Ercolani, Ronald J; Sahoo, Malaya K et al. (2014) Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. Antimicrob Agents Chemother 58:4697-702
Webel, Rike; Hakki, Morgan; Prichard, Mark N et al. (2014) Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibility. J Virol 88:4776-85
Chou, Sunwen; Komazin-Meredith, Gloria; Williams, John D et al. (2014) Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives. Antimicrob Agents Chemother 58:1809-12
Chou, Sunwen; Boivin, Guy; Ives, Jane et al. (2014) Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial. J Infect Dis 209:1219-26
Chou, Sunwen; Ercolani, Ronald J; Marousek, Gail et al. (2013) Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. Antimicrob Agents Chemother 57:3375-9
Chou, Sunwen; Hakki, Morgan; Villano, Stephen (2012) Effects on maribavir susceptibility of cytomegalovirus UL97 kinase ATP binding region mutations detected after drug exposure in vitro and in vivo. Antiviral Res 95:88-92
Chou, Sunwen; Marousek, Gail; Bowlin, Terry L (2012) Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. Antimicrob Agents Chemother 56:197-201
Goldberg, Miri D; Honigman, Alik; Weinstein, Jacob et al. (2011) Human cytomegalovirus UL97 kinase and nonkinase functions mediate viral cytoplasmic secondary envelopment. J Virol 85:3375-84
Chou, Sunwen; Bowlin, Terry L (2011) Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. Antimicrob Agents Chemother 55:382-4

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