Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI042236-06S1
Application #
6909390
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Alexander, William A
Project Start
1998-02-01
Project End
2008-12-31
Budget Start
2004-07-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$30,757
Indirect Cost
Name
Washington University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
May, John F; Groisman, Eduardo A (2013) Conflicting roles for a cell surface modification in Salmonella. Mol Microbiol 88:970-83
Townsend 2nd, Guy E; Raghavan, Varsha; Zwir, Igor et al. (2013) Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems. Proc Natl Acad Sci U S A 110:E161-9
Choi, Jeongjoon; Groisman, Eduardo A (2013) The lipopolysaccharide modification regulator PmrA limits Salmonella virulence by repressing the type three-secretion system Spi/Ssa. Proc Natl Acad Sci U S A 110:9499-504
Groisman, Eduardo A; Hollands, Kerry; Kriner, Michelle A et al. (2013) Bacterial Mg2+ homeostasis, transport, and virulence. Annu Rev Genet 47:625-46
Kato, Akinori; Chen, H Deborah; Latifi, Tammy et al. (2012) Reciprocal control between a bacterium's regulatory system and the modification status of its lipopolysaccharide. Mol Cell 47:897-908
Yeo, Won-Sik; Zwir, Igor; Huang, Henry V et al. (2012) Intrinsic negative feedback governs activation surge in two-component regulatory systems. Mol Cell 45:409-21
Chen, H Deborah; Jewett, Mollie W; Groisman, Eduardo A (2012) An allele of an ancestral transcription factor dependent on a horizontally acquired gene product. PLoS Genet 8:e1003060
Jarvik, Tyler; Smillie, Chris; Groisman, Eduardo A et al. (2010) Short-term signatures of evolutionary change in the Salmonella enterica serovar typhimurium 14028 genome. J Bacteriol 192:560-7
Mitrophanov, Alexander Y; Groisman, Eduardo A (2010) Response acceleration in post-translationally regulated genetic circuits. J Mol Biol 396:1398-409
Raghavan, Varsha; Groisman, Eduardo A (2010) Orphan and hybrid two-component system proteins in health and disease. Curr Opin Microbiol 13:226-31

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