Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053531-02
Application #
6768789
Study Section
Biochemistry Study Section (BIO)
Program Officer
Park, Eun-Chung
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$321,226
Indirect Cost

  Institution

Name
Pennsylvania State University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
003403953
City
University Park
State
PA
Country
United States
Zip Code
16802

  Publications

Banerjee, Sravani; Aponte-Diaz, David; Yeager, Calvin et al. (2018) Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. PLoS Pathog 14:e1007086
Oh, Hyung S; Banerjee, Sravani; Aponte-Diaz, David et al. (2018) Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides. PLoS Pathog 14:e1007036
Huang, Peng-Nien; Jheng, Jia-Rong; Arnold, Jamie J et al. (2017) UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication. PLoS Pathog 13:e1006375
Shengjuler, Djoshkun; Sun, Simou; Cremer, Paul S et al. (2017) PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions. J Vis Exp :
Shengjuler, Djoshkun; Chan, Yan Mei; Sun, Simou et al. (2017) The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain. Structure 25:1875-1886.e7
Chan, Yan M; Moustafa, Ibrahim M; Arnold, Jamie J et al. (2016) Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein. Structure 24:509-517
Kolli, Swapna; Meng, Xiangzhi; Wu, Xiang et al. (2015) Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication. J Virol 89:2209-19
Moustafa, Ibrahim M; Gohara, David W; Uchida, Akira et al. (2015) Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome? Viruses 7:5962-86
Liu, Yen-Chin; Kuo, Rei-Lin; Lin, Jing-Yi et al. (2014) Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8. PLoS Pathog 10:e1004199
Graci, Jason D; Gnadig, Nina F; Galarraga, Jessica E et al. (2012) Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis. J Virol 86:2869-73

Showing the most recent 10 out of 25 publications