Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI055502-02
Application #
6758534
Study Section
Experimental Immunology Study Section (EI)
Program Officer
Winter, David B
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$367,875
Indirect Cost
Name
Yale University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Okin, Daniel; Medzhitov, Ruslan (2016) The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia. Cell 165:343-56
Schenten, Dominik; Nish, Simone A; Yu, Shuang et al. (2014) Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity 40:78-90
Bezbradica, Jelena S; Rosenstein, Rachel K; DeMarco, Richard A et al. (2014) A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol 15:333-42
Chang, Pamela V; Hao, Liming; Offermanns, Stefan et al. (2014) The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc Natl Acad Sci U S A 111:2247-52
Nish, Simone A; Schenten, Dominik; Wunderlich, F Thomas et al. (2014) T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife 3:e01949
Palm, Noah W; Medzhitov, Ruslan (2013) Role of the inflammasome in defense against venoms. Proc Natl Acad Sci U S A 110:1809-14
Kotas, Maya E; Jurczak, Michael J; Annicelli, Charles et al. (2013) Role of caspase-1 in regulation of triglyceride metabolism. Proc Natl Acad Sci U S A 110:4810-5
Palm, Noah W; Rosenstein, Rachel K; Yu, Shuang et al. (2013) Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity 39:976-85
Gao, Yan; Nish, Simone A; Jiang, Ruoyi et al. (2013) Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity 39:722-32
Jamieson, Amanda M; Pasman, Lesley; Yu, Shuang et al. (2013) Role of tissue protection in lethal respiratory viral-bacterial coinfection. Science 340:1230-4

Showing the most recent 10 out of 29 publications