Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR010728-28
Application #
2078269
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-02-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
28
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Castor, C William; Kotlyar, Alina; Edwards, Brian E (2002) Connective tissue activation XXXVIII: heparin/heparanase activity of human platelets resides in a high molecular weight protein, not in connective tissue activating peptide III. J Rheumatol 29:2337-44
Castor, C W; Smith, E M; Bignall, M C et al. (1997) Connective tissue activation. XXXVII. Effects of cytokine combinations, implications for an integrated cytokine network. J Rheumatol 24:2080-9
Cabral, A R; Castor, C W (1996) Connective tissue activating peptide-V and CD59: a molecule in search of a job. J Rheumatol 23:1126-9
Castor, C W; Andrews, P C; Swartz, R D et al. (1993) Connective tissue activation. XXXVI. The origin, variety, distribution, and biologic fate of connective tissue activating peptide-III isoforms: characteristics in patients with rheumatic, renal, and arterial disease. Arthritis Rheum 36:1142-53
Castor, C W; Smith, E M; Hossler, P A et al. (1992) Connective tissue activation. XXXV. Detection of connective tissue activating peptide-III isoforms in synovium from osteoarthritis and rheumatoid arthritis patients: patterns of interaction with other synovial cytokines in cell culture. Arthritis Rheum 35:783-93
Tai, P K; Liao, J F; Hossler, P A et al. (1992) Regulation of glucose transporters by connective tissue activating peptide-III isoforms. J Biol Chem 267:19579-86
Castor, C W; Smith, E M; Bignall, M C et al. (1991) Preparation and bioassay of connective tissue activating peptide III and its isoforms. Methods Enzymol 198:405-16
Castor, C W; Walz, D A; Johnson, P H et al. (1990) Connective tissue activation. XXXIV: Effects of proteolytic processing on the biologic activities of CTAP-III. J Lab Clin Med 116:516-26
Sisson, T H; Castor, C W (1990) An improved method for immobilizing IgG antibodies on protein A-agarose. J Immunol Methods 127:215-20
Castor, C W; Walz, D A; Ragsdale, C G et al. (1989) Connective tissue activation. XXXIII. Biologically active cleavage products of CTAP-III from human platelets. Biochem Biophys Res Commun 163:1071-8

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