Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR011476-27
Application #
2078281
Study Section
Pathology A Study Section (PTHA)
Project Start
1976-06-25
Project End
1997-04-30
Budget Start
1995-07-10
Budget End
1997-04-30
Support Year
27
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Mannik, Mart; Merrill, Cynthia E; Stamps, Louis D et al. (2003) Multiple autoantibodies form the glomerular immune deposits in patients with systemic lupus erythematosus. J Rheumatol 30:1495-504
Kohro-Kawata, Junko; Wener, Mark H; Mannik, Mart (2002) The effect of high salt concentration on detection of serum immune complexes and autoantibodies to C1q in patients with systemic lupus erythematosus. J Rheumatol 29:84-9
Mannik, M; Merrill, C E; Wener, M H (2000) Antibodies to human myeloperoxidase in glomerular immune deposits of systemic lupus erythematosus. Lupus 9:607-13
Mannik, M; Wener, M H (1997) Deposition of antibodies to the collagen-like region of C1q in renal glomeruli of patients with proliferative lupus glomerulonephritis. Arthritis Rheum 40:1504-11
Mannik, M (1996) Presence of covalent bonds between immune deposits and other macromolecules in murine renal glomeruli. Clin Exp Immunol 103:285-8
Gauthier, V J; Tyler, L N; Mannik, M (1996) Blood clearance kinetics and liver uptake of mononucleosomes in mice. J Immunol 156:1151-6
Uwatoko, S; Mannik, M; Oppliger, I R et al. (1995) C1q-binding immunoglobulin G in MRL/l mice consists of immune complexes containing antibodies to DNA. Clin Immunol Immunopathol 75:140-6
Mannik, M; Kobayashi, M; Alpers, C E et al. (1993) Antigens of varying size persist longer in subepithelial than in subendothelial immune deposits in murine glomeruli. J Immunol 150:2062-71
Uwatoko, S; Gauthier, V J; Mannik, M (1991) Autoantibodies to the collagen-like region of C1Q deposit in glomeruli via C1Q in immune deposits. Clin Immunol Immunopathol 61:268-73
Mannik, M; Person, R E (1991) New antigenic determinants revealed on human IgG by binding to immunoblotting membranes [corrected] J Immunol Methods 144:265-7

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