Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR036294-18
Application #
2079137
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1986-01-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Physiology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
DeRosimo, J F; Washabaugh, C H; Ontell, M P et al. (2000) Enhancement of adult muscle regeneration by primary myoblast transplantation. Cell Transplant 9:369-77
Chen, H H; Mack, L M; Choi, S Y et al. (1999) DNA from both high-capacity and first-generation adenoviral vectors remains intact in skeletal muscle. Hum Gene Ther 10:365-73
Floyd Jr, S S; Clemens, P R; Ontell, M R et al. (1998) Ex vivo gene transfer using adenovirus-mediated full-length dystrophin delivery to dystrophic muscles. Gene Ther 5:19-30
Yang, J; Kelly, R; Daood, M et al. (1998) Alteration in myosatellite cell commitment with muscle maturation. Dev Dyn 211:141-52
Chen, H H; Mack, L M; Kelly, R et al. (1997) Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci U S A 94:1645-50
Yang, J; Ontell, M P; Kelly, R et al. (1997) Limitations of nls beta-galactosidase as a marker for studying myogenic lineage or the efficacy of myoblast transfer. Anat Rec 248:40-50
Arcila, M E; Ameredes, B T; DeRosimo, J F et al. (1997) Mass and functional capacity of regenerating muscle is enhanced by myoblast transfer. J Neurobiol 33:185-98
Sopper, M M; Hauschka, S D; Hoffman, E et al. (1994) Gene complementation using myoblast transfer into fetal muscle. Gene Ther 1:108-13
Ontell, M P; Hughes, D; Hauschka, S D et al. (1992) Transient neonatal denervation alters the proliferative capacity of myosatellite cells in dystrophic (129ReJdy/dy) muscle. J Neurobiol 23:407-19
Ontell, M P; Moschella, M C; Schiaffino, S et al. (1992) Modification of the dystrophic phenotype after transient neonatal denervation: role of MHC isoforms. J Neurobiol 23:751-65

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