Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR038889-01A2
Application #
3158881
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-12-01
Project End
1993-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Hospital for Special Surgery
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10021
Issuree, Priya Darshinee A; Maretzky, Thorsten; McIlwain, David R et al. (2013) iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. J Clin Invest 123:928-32
Lynch, Anne M; Eckel, Robert H; Murphy, James R et al. (2012) Prepregnancy obesity and complement system activation in early pregnancy and the subsequent development of preeclampsia. Am J Obstet Gynecol 206:428.e1-8
Qing, Xiaoping; Koo, Gloria C; Salmon, Jane E (2012) Complement regulates conventional DC-mediated NK-cell activation by inducing TGF-?1 in Gr-1+ myeloid cells. Eur J Immunol 42:1723-34
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Lynch, Anne M; Gibbs, Ronald S; Murphy, James R et al. (2011) Early elevations of the complement activation fragment C3a and adverse pregnancy outcomes. Obstet Gynecol 117:75-83
Andrade, Danieli; Redecha, Patricia B; Vukelic, Milena et al. (2011) Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB-RAG-2-/- IL-2R?-/- mice: a promising model for studying human disease. Arthritis Rheum 63:2764-73
Lynch, A M; Salmon, J E (2010) Dysregulated complement activation as a common pathway of injury in preeclampsia and other pregnancy complications. Placenta 31:561-7
Salmon, J E; de Groot, P G (2008) Pathogenic role of antiphospholipid antibodies. Lupus 17:405-11
Salmon, Jane E; Girardi, Guillermina (2008) Antiphospholipid antibodies and pregnancy loss: a disorder of inflammation. J Reprod Immunol 77:51-6
Stefanescu, Radu N; Olferiev, Mikhail; Liu, Yi et al. (2004) Inhibitory Fc gamma receptors: from gene to disease. J Clin Immunol 24:315-26

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