Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR039979-06
Application #
2079796
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1989-06-15
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Barnes, M G; Aronow, B J; Luyrink, L K et al. (2004) Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis. Rheumatology (Oxford) 43:973-9
Scola, Michael P; Thompson, Susan D; Brunner, Hermine I et al. (2002) Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue. J Rheumatol 29:369-78
Prahalad, S; Kingsbury, D J; Griffin, T A et al. (2001) Polymorphism in the MHC-encoded LMP7 gene: association with JRA without functional significance for immunoproteasome assembly. J Rheumatol 28:2320-5
Thompson, S D; Luyrink, L K; Graham, T B et al. (2001) Chemokine receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4:IFN-gamma mRNA ratios. J Immunol 166:6899-906
Scola, M P; Imagawa, T; Boivin, G P et al. (2001) Expression of angiogenic factors in juvenile rheumatoid arthritis: correlation with revascularization of human synovium engrafted into SCID mice. Arthritis Rheum 44:794-801
Prahalad, S; Ryan, M H; Shear, E S et al. (2000) Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs. Arthritis Rheum 43:2335-8
Glass, D N; Giannini, E H (1999) Juvenile rheumatoid arthritis as a complex genetic trait. Arthritis Rheum 42:2261-8
Murray, K J; Moroldo, M B; Donnelly, P et al. (1999) Age-specific effects of juvenile rheumatoid arthritis-associated HLA alleles. Arthritis Rheum 42:1843-53
Thompson, S D; Murray, K J; Grom, A A et al. (1998) Comparative sequence analysis of the human T cell receptor beta chain in juvenile rheumatoid arthritis and juvenile spondylarthropathies: evidence for antigenic selection of T cells in the synovium. Arthritis Rheum 41:482-97
Murray, K J; Grom, A A; Thompson, S D et al. (1998) Contrasting cytokine profiles in the synovium of different forms of juvenile rheumatoid arthritis and juvenile spondyloarthropathy: prominence of interleukin 4 in restricted disease. J Rheumatol 25:1388-98

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