Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR040135-06
Application #
2079859
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1990-08-31
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Banda, Nirmal K; Guthridge, Carla; Sheppard, Devon et al. (2005) Intracellular IL-1 receptor antagonist type 1 inhibits IL-1-induced cytokine production in keratinocytes through binding to the third component of the COP9 signalosome. J Immunol 174:3608-16
Ross, Aron D; Banda, Nirmal K; Muggli, Michele et al. (2004) Enhancement of collagen-induced arthritis in mice genetically deficient in extracellular superoxide dismutase. Arthritis Rheum 50:3702-11
Arend, William P; Gabay, Cem (2004) Cytokines in the rheumatic diseases. Rheum Dis Clin North Am 30:41-67, v-vi
Banda, Nirmal K; Kraus, Damian M; Muggli, Michele et al. (2003) Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y. J Immunol 171:2109-15
Palmer, Gaby; Talabot-Ayer, Dominique; Szalay-Quinodoz, Ildiko et al. (2003) Mice transgenic for intracellular interleukin-1 receptor antagonist type 1 are protected from collagen-induced arthritis. Eur J Immunol 33:434-40
Banda, Nirmal K; Kraus, Damian; Vondracek, Andrea et al. (2002) Mechanisms of effects of complement inhibition in murine collagen-induced arthritis. Arthritis Rheum 46:3065-75
Gabay, C; Gigley, J; Sipe, J et al. (2001) Production of IL-1 receptor antagonist by hepatocytes is regulated as an acute-phase protein in vivo. Eur J Immunol 31:490-9
Arend, W P (2001) The innate immune system in rheumatoid arthritis. Arthritis Rheum 44:2224-34
Gabay, C; Marinova-Mutafchieva, L; Williams, R O et al. (2001) Increased production of intracellular interleukin-1 receptor antagonist type I in the synovium of mice with collagen-induced arthritis: a possible role in the resolution of arthritis. Arthritis Rheum 44:451-62
Arend, W P (2001) Physiology of cytokine pathways in rheumatoid arthritis. Arthritis Rheum 45:101-6

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