Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR040310-07
Application #
2079958
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1990-03-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Kugyelka, Reka; Kohl, Zoltan; Olasz, Katalin et al. (2016) Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis. Mediators Inflamm 2016:6145810
Haynes, Katelin R; Pettit, Allison R; Duan, Ran et al. (2012) Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Res Ther 14:R253
Kis-Toth, Katalin; Radacs, Marianna; Olasz, Katalin et al. (2012) Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice. Int Immunol 24:507-17
Olasz, K; Boldizsar, F; Kis-Toth, K et al. (2012) T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice. Clin Exp Immunol 167:346-55
Besenyei, Timea; Kadar, Andras; Tryniszewska, Beata et al. (2012) Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models. Clin Dev Immunol 2012:284751
Kezic, Jelena M; Davey, Michael P; Glant, Tibor T et al. (2012) Interferon-? regulates discordant mechanisms of uveitis versus joint and axial disease in a murine model resembling spondylarthritis. Arthritis Rheum 64:762-71
Nagyeri, Gyorgy; Radacs, Marianna; Ghassemi-Nejad, Sheida et al. (2011) TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin. J Biol Chem 286:23559-69
Ghassemi-Nejad, S; Kobezda, T; Rauch, T A et al. (2011) Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis. Osteoarthritis Cartilage 19:458-65
Glant, Tibor T; Radacs, Marianna; Nagyeri, Gyorgy et al. (2011) Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis. Arthritis Rheum 63:1312-21
Angyal, Adrienn; Egelston, Colt; Kobezda, Tamas et al. (2010) Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints. Arthritis Res Ther 12:R44

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