Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR040352-04A1
Application #
2006199
Study Section
Special Emphasis Panel (ZRG2-ET-1 (03))
Project Start
1992-05-01
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Spring, Bryan Q; Abu-Yousif, Adnan O; Palanisami, Akilan et al. (2014) Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates. Proc Natl Acad Sci U S A 111:E933-42
Spring, Bryan Q; Palanisami, Akilan; Hasan, Tayyaba (2014) Microscale receiver operating characteristic analysis of micrometastasis recognition using activatable fluorescent probes indicates leukocyte imaging as a critical factor to enhance accuracy. J Biomed Opt 19:066006
Abu-Yousif, Adnan O; Moor, Anne C E; Zheng, Xiang et al. (2012) Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells. Cancer Lett 321:120-7
Rizvi, Imran; Celli, Jonathan P; Evans, Conor L et al. (2010) Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res 70:9319-28
Celli, Jonathan P; Rizvi, Imran; Evans, Conor L et al. (2010) Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model. J Biomed Opt 15:051603
Evans, Conor L; Rizvi, Imran; Hasan, Tayyaba et al. (2009) In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging. Opt Express 17:8892-906
Casas, Adriana; Di Venosa, Gabriela; Vanzulli, Silvia et al. (2008) Decreased metastatic phenotype in cells resistant to aminolevulinic acid-photodynamic therapy. Cancer Lett 271:342-51
Verma, Sarika; Watt, Gregory M; Mai, Zhiming et al. (2007) Strategies for enhanced photodynamic therapy effects. Photochem Photobiol 83:996-1005
Casas, Adriana; Perotti, Christian; Ortel, Bernhard et al. (2006) Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells. Int J Oncol 29:397-405
Solban, Nicolas; Rizvi, Imran; Hasan, Tayyaba (2006) Targeted photodynamic therapy. Lasers Surg Med 38:522-31

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