Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
7R01AR042309-03
Application #
2081479
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1993-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Bhattacharyya, Swati; Varga, John (2018) Endogenous ligands of TLR4 promote unresolving tissue fibrosis: Implications for systemic sclerosis and its targeted therapy. Immunol Lett 195:9-17
Cooper, John G; Jeong, Su Ji; McGuire, Tammy L et al. (2018) Fibronectin EDA forms the chronic fibrotic scar after contusive spinal cord injury. Neurobiol Dis 116:60-68
Korman, Benjamin; Marangoni, Roberta Goncalves; Lord, Gabriel et al. (2018) Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis. Arthritis Res Ther 20:145
Marangoni, Roberta G; Masui, Yuri; Fang, Feng et al. (2017) Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target. Sci Rep 7:4397
Wei, Jun; Zhu, Hongyan; Lord, Gabriel et al. (2017) Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative. Transl Res 183:71-86.e1
Bhattacharyya, Swati; Wang, Wenxia; Morales-Nebreda, Luisa et al. (2016) Tenascin-C drives persistence of organ fibrosis. Nat Commun 7:11703
Reinke, Lauren; Lam, Anna P; Flozak, Annette S et al. (2016) Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and ?-catenin signaling. Biochem Biophys Res Commun 470:606-612
Bhattacharyya, Swati; Wang, Wenxia; Graham, Lauren Van Duyn et al. (2016) A20 suppresses canonical Smad-dependent fibroblast activation: novel function for an endogenous inflammatory modulator. Arthritis Res Ther 18:216
Taroni, Jaclyn N; Martyanov, Viktor; Huang, Chiang-Ching et al. (2015) Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures. Arthritis Res Ther 17:194
Lakota, Katja; Carns, Mary; Podlusky, Sofia et al. (2015) Serum amyloid A is a marker for pulmonary involvement in systemic sclerosis. PLoS One 10:e0110820

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