Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR044474-01
Application #
2083993
Study Section
Metabolism Study Section (MET)
Project Start
1996-07-20
Project End
1999-06-30
Budget Start
1996-07-20
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Manjarín, Rodrigo; Columbus, Daniel A; Solis, Jessica et al. (2018) Short- and long-term effects of leucine and branched-chain amino acid supplementation of a protein- and energy-reduced diet on muscle protein metabolism in neonatal pigs. Amino Acids 50:943-959
Manjarín, Rodrigo; Columbus, Daniel A; Suryawan, Agus et al. (2016) Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs. Amino Acids 48:257-267
Manjarín, Rodrigo; Suryawan, Agus; Koo, Sue J et al. (2016) Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs. Pediatr Res 80:744-752
Hernandez-García, Adriana; Manjarín, Rodrigo; Suryawan, Agus et al. (2016) Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia. Pediatr Res 80:448-51
Hernandez-García, Adriana D; Columbus, Daniel A; Manjarín, Rodrigo et al. (2016) Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia. Am J Physiol Endocrinol Metab 311:E791-E801
Columbus, Daniel A; Steinhoff-Wagner, Julia; Suryawan, Agus et al. (2015) Impact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs. Am J Physiol Endocrinol Metab 309:E601-10
Layman, Donald K; Anthony, Tracy G; Rasmussen, Blake B et al. (2015) Defining meal requirements for protein to optimize metabolic roles of amino acids. Am J Clin Nutr 101:1330S-1338S
Columbus, Daniel A; Fiorotto, Marta L; Davis, Teresa A (2015) Leucine is a major regulator of muscle protein synthesis in neonates. Amino Acids 47:259-70
Reynolds, Lawrence P; Wulster-Radcliffe, Meghan C; Aaron, Debra K et al. (2015) Importance of Animals in Agricultural Sustainability and Food Security. J Nutr 145:1377-9
Davis, Teresa A; Fiorotto, Marta L; Suryawan, Agus (2015) Bolus vs. continuous feeding to optimize anabolism in neonates. Curr Opin Clin Nutr Metab Care 18:102-8

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