The risk of occupationally-related low-back disorders (LBD) in women is twice that for men. In general, LBDs are the leading cause of lost work days and the most costly occupational safety and health problem facing industry today. As the workforce approaches gender equity in numbers and occupational roles, the rate of LBDs will rise proportionally. Unfortunately, the influence of gender as a risk factor for musculoskeletal injury and LBD is poorly understood. Low-back pain develops when spinal load repetitively exceeds injury tolerance. Although there is no evidence suggesting spinal load is greater for women than men, there are studies indicating possible gender differences in spinal stability. Stability determines the maximum load the spine can withstand safely, i.e. injury tolerance. Spinal shape, muscle recruitment, muscle stiffness, and reaction mechanics contribute to spinal stability. There is limited research suggesting gender differences in these factors. Thus, men and women are exposed to similar spinal loads during manual materials handling (MMH) tasks, but women may have a lower tolerance to spinal load resulting in a higher risk of occupational LBD. Size and strength are obvious characteristics differentiating men and women from a MMH standpoint. This difference results in greater potential for fatigue in women compared to equivalently conditioned men. Fatigue has been shown to influence spinal shape, muscle recruitment patterns, muscle stiffness, and reaction mechanics. Hence, fatigue may be related to spinal stability and associated LBD risk. The potential for musculoskeletal instability and LBD injury in women is enhanced in fatiguing environments. To explain the increased risk of occupational LBD we propose three hypotheses. 1) A gender difference exists in spinal stability factors including dynamic spinal shape, reflex time and magnitude, muscle stiffness (elasticity), and muscle recruitment patterns (co-contraction). 2) Fatigue enhances the gender differences in spinal stability factors. 3) These musculoskeletal factors contribute to gender differences in the stability of the spine during lifting tasks. We propose to quantify these musculoskeletal factors as a function of gender and fatigue under controlled and MMH lifting conditions. Musculoskeletal stability and associated injury tolerance will be modeled from these data as a function of gender and fatigue. Results will demonstrate how workplace factors influence women differently than men and identify injury mechanisms explaining increased risk in women. The goal of this research is to permit greater inclusion of women in the workforce while controlling the risk of occupational LBD.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR046111-01
Application #
2848342
Study Section
Safety and Occupational Health Study Section (SOH)
Project Start
1998-09-30
Project End
2001-08-31
Budget Start
1998-09-30
Budget End
1999-08-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Virginia
Department
Orthopedics
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
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Miller, Emily M; Slota, Gregory P; Agnew, Michael J et al. (2010) Females exhibit shorter paraspinal reflex latencies than males in response to sudden trunk flexion perturbations. Clin Biomech (Bristol, Avon) 25:541-5
Groth, Kevin M; Granata, Kevin P (2008) The viscoelastic standard nonlinear solid model: predicting the response of the lumbar intervertebral disk to low-frequency vibrations. J Biomech Eng 130:031005
Granata, K P; Gottipati, P (2008) Fatigue influences the dynamic stability of the torso. Ergonomics 51:1258-71
Franklin, Timothy C; Granata, Kevin P; Madigan, Michael L et al. (2008) Linear time delay methods and stability analyses of the human spine. Effects of neuromuscular reflex response. IEEE Trans Neural Syst Rehabil Eng 16:353-9
Moorhouse, Kevin M; Granata, Kevin P (2007) Role of reflex dynamics in spinal stability: intrinsic muscle stiffness alone is insufficient for stability. J Biomech 40:1058-65
Granata, K P; Rogers, E (2007) Torso flexion modulates stiffness and reflex response. J Electromyogr Kinesiol 17:384-92
Franklin, Timothy C; Granata, Kevin P (2007) Role of reflex gain and reflex delay in spinal stability--a dynamic simulation. J Biomech 40:1762-7
Rogers, Ellen L; Granata, Kevin P (2006) Disturbed paraspinal reflex following prolonged flexion-relaxation and recovery. Spine (Phila Pa 1976) 31:839-45
Granata, Kevin P; England, Scott A (2006) Stability of dynamic trunk movement. Spine 31:E271-6

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