Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA011944-29
Application #
6512507
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Okano, Paul
Project Start
1977-09-30
Project End
2004-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
29
Fiscal Year
2002
Total Cost
$302,738
Indirect Cost
Name
Baylor College of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Medina, Daniel; Kittrell, Frances (2005) Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia. J Cell Sci 118:123-7
Kong, Gu; Chua, Steven S; Yijun, Yi et al. (2002) Functional analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during development. Oncogene 21:7214-25
Medina, Daniel (2002) Biological and molecular characteristics of the premalignant mouse mammary gland. Biochim Biophys Acta 1603:1-9
Said, T K; Moraes, R C; Singh, U et al. (2001) Cyclin-dependent kinase (cdk) inhibitors/cdk4/cdk2 complexes in early stages of mouse mammary preneoplasia. Cell Growth Differ 12:285-95
Said, T K; Moraes, R C; Sinha, R et al. (2001) Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth. Breast Cancer Res 3:122-33
Medina, D (2000) The preneoplastic phenotype in murine mammary tumorigenesis. J Mammary Gland Biol Neoplasia 5:393-407
Lydon, J P; Ge, G; Kittrell, F S et al. (1999) Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res 59:4276-84
Said, T K; Medina, D (1998) Interaction of retinoblastoma protein and D cyclins during cell-growth inhibition by hexamethylenebisacetamide in TM2H mouse epithelial cells. Mol Carcinog 22:128-43
Said, T K; Conneely, O M; Medina, D et al. (1997) Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology 138:3933-9
Medina, D (1996) The mammary gland: a unique organ for the study of development and tumorigenesis. J Mammary Gland Biol Neoplasia 1:5-19

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