Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA013410-19S1
Application #
2086137
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1976-06-01
Project End
1995-08-31
Budget Start
1995-03-01
Budget End
1995-08-31
Support Year
19
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Tufts University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Soto, Ana M; Maffini, Maricel V; Schaeberle, Cheryl M et al. (2006) Strengths and weaknesses of in vitro assays for estrogenic and androgenic activity. Best Pract Res Clin Endocrinol Metab 20:15-33
Soto, Ana M; Sonnenschein, Carlos (2004) The somatic mutation theory of cancer: growing problems with the paradigm? Bioessays 26:1097-107
Powell, Charles E; Soto, Ana M; Michaelson, Cheryl L et al. (2003) Characterization of a plasma membrane-resident albumin-binding protein associated with the proliferation of estrogen-target, serum-sensitive cells. Steroids 68:487-96
Maffini, Maricel V; Geck, Peter; Powell, Charles E et al. (2002) Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate. Endocrinology 143:2708-14
Powell, C E; Soto, A M; Sonnenschein, C (2001) Identification and characterization of membrane estrogen receptor from MCF7 estrogen-target cells. J Steroid Biochem Mol Biol 77:97-108
Sonnenschein, C; Soto, A M (2000) Somatic mutation theory of carcinogenesis: why it should be dropped and replaced. Mol Carcinog 29:205-11
Geck, P; Maffini, M V; Szelei, J et al. (2000) Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator. Proc Natl Acad Sci U S A 97:10185-90
Szelei, J; Soto, A M; Geck, P et al. (2000) Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer. J Steroid Biochem Mol Biol 72:89-102
Geck, P; Szelei, J; Jimenez, J et al. (1999) Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus. J Steroid Biochem Mol Biol 68:41-50
Soto, A M; Michaelson, C L; Prechtl, N V et al. (1998) Assays to measure estrogen and androgen agonists and antagonists. Adv Exp Med Biol 444:9-23;discussion 23-8

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