Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA020081-20
Application #
2086801
Study Section
Virology Study Section (VR)
Project Start
1977-05-01
Project End
2001-05-31
Budget Start
1996-08-15
Budget End
1997-05-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cornell University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Dick, Robert A; Kamynina, Elena; Vogt, Volker M (2013) Effect of multimerization on membrane association of Rous sarcoma virus and HIV-1 matrix domain proteins. J Virol 87:13598-608
Dick, Robert A; Goh, Shih Lin; Feigenson, Gerald W et al. (2012) HIV-1 Gag protein can sense the cholesterol and acyl chain environment in model membranes. Proc Natl Acad Sci U S A 109:18761-6
Chan, Jany; Dick, Robert A; Vogt, Volker M (2011) Rous sarcoma virus gag has no specific requirement for phosphatidylinositol-(4,5)-bisphosphate for plasma membrane association in vivo or for liposome interaction in vitro. J Virol 85:10851-60
Taylor, Gwen M; Ma, Lixin; Vogt, Volker M et al. (2010) NMR relaxation studies of an RNA-binding segment of the rous sarcoma virus gag polyprotein in free and bound states: a model for autoinhibition of assembly. Biochemistry 49:4006-17
de Marco, Alex; Davey, Norman E; Ulbrich, Pavel et al. (2010) Conserved and variable features of Gag structure and arrangement in immature retrovirus particles. J Virol 84:11729-36
Dilley, Kari A; Gregory, Devon; Johnson, Marc C et al. (2010) An LYPSL late domain in the gag protein contributes to the efficient release and replication of Rous sarcoma virus. J Virol 84:6276-87
Jorgenson, Rebecca L; Vogt, Volker M; Johnson, Marc C (2009) Foreign glycoproteins can be actively recruited to virus assembly sites during pseudotyping. J Virol 83:4060-7
Keller, Paul W; Johnson, Marc C; Vogt, Volker M (2008) Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding. J Virol 82:6788-97
Zhou, Jing; Bean, Rebecca L; Vogt, Volker M et al. (2007) Solution structure of the Rous sarcoma virus nucleocapsid protein: muPsi RNA packaging signal complex. J Mol Biol 365:453-67
Saad, Jamil S; Kim, Andrew; Ghanam, Ruba H et al. (2007) Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch. Protein Sci 16:1793-7

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