Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA021776-19A1
Application #
2086982
Study Section
Experimental Virology Study Section (EVR)
Project Start
1977-09-01
Project End
2001-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Fan, Qing; Kopp, Sarah J; Byskosh, Nina C et al. (2018) Natural Selection of Glycoprotein B Mutations That Rescue the Small-Plaque Phenotype of a Fusion-Impaired Herpes Simplex Virus Mutant. MBio 9:
Edwards, Rebecca G; Longnecker, Richard (2017) Herpesvirus Entry Mediator and Ocular Herpesvirus Infection: More than Meets the Eye. J Virol 91:
Fan, Qing; Kopp, Sarah; Connolly, Sarah A et al. (2017) Mapping sites of herpes simplex virus type 1 glycoprotein D that permit insertions and impact gD and gB receptors usage. Sci Rep 7:43712
Fan, Qing; Kopp, Sarah J; Connolly, Sarah A et al. (2017) Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype. MBio 8:
Wilcox, Douglas R; Longnecker, Richard (2016) The Herpes Simplex Virus Neurovirulence Factor ?34.5: Revealing Virus-Host Interactions. PLoS Pathog 12:e1005449
Wilcox, Douglas R; Folmsbee, Stephen S; Muller, William J et al. (2016) The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis. MBio 7:e00437-16
Wilcox, Douglas R; Muller, William J; Longnecker, Richard (2015) HSV targeting of the host phosphatase PP1? is required for disseminated disease in the neonate and contributes to pathogenesis in the brain. Proc Natl Acad Sci U S A 112:E6937-44
Lajko, Michelle; Haddad, Alexander F; Robinson, Carolyn A et al. (2015) Using proximity biotinylation to detect herpesvirus entry glycoprotein interactions: Limitations for integral membrane glycoproteins. J Virol Methods 221:81-9
Wilcox, Douglas R; Wadhwani, Nitin R; Longnecker, Richard et al. (2015) Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults. PLoS Pathog 11:e1004580
Fan, Qing; Longnecker, Richard; Connolly, Sarah A (2015) A Functional Interaction between Herpes Simplex Virus 1 Glycoprotein gH/gL Domains I and II and gD Is Defined by Using Alphaherpesvirus gH and gL Chimeras. J Virol 89:7159-69

Showing the most recent 10 out of 63 publications