Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA022090-09
Application #
3165711
Study Section
Immunobiology Study Section (IMB)
Project Start
1977-09-01
Project End
1986-01-31
Budget Start
1985-06-01
Budget End
1986-01-31
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
Graduate Schools
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Nathan, C; Squires, K; Griffo, W et al. (1990) Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon gamma. J Exp Med 172:1509-12
Ding, A; Nathan, C (1988) Analysis of the nonfunctional respiratory burst in murine Kupffer cells. J Exp Med 167:1154-70
Vadhan-Raj, S; Al-Katib, A; Bhalla, R et al. (1986) Phase I trial of recombinant interferon gamma in cancer patients. J Clin Oncol 4:137-46
Nathan, C F; Kaplan, G; Levis, W R et al. (1986) Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. N Engl J Med 315:6-15
Nathan, C F (1986) Macrophage activation: some questions. Ann Inst Pasteur Immunol 137C:345-51
Nathan, C F; Tsunawaki, S (1986) Secretion of toxic oxygen products by macrophages: regulatory cytokines and their effects on the oxidase. Ciba Found Symp 118:211-30
Tsunawaki, S; Nathan, C F (1986) Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage. J Biol Chem 261:11563-70
Vadhan-Raj, S; Nathan, C F; Sherwin, S A et al. (1986) Phase I trial of recombinant interferon gamma by 1-hour i.v. infusion. Cancer Treat Rep 70:609-14
Gabay, J E; Heiple, J M; Cohn, Z A et al. (1986) Subcellular location and properties of bactericidal factors from human neutrophils. J Exp Med 164:1407-21
Tsunawaki, S; Nathan, C F (1986) Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium. J Exp Med 164:1319-31

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