Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA024220-18
Application #
2087233
Study Section
Experimental Virology Study Section (EVR)
Project Start
1978-09-01
Project End
2001-01-31
Budget Start
1996-04-15
Budget End
1997-01-31
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Pathology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Yi, Chae-ryun; Rosenberg, Naomi (2008) Mutations affecting the MA portion of the v-Abl protein reveal a conserved role of Gag in Abelson murine leukemia virus (MLV) and Moloney MLV. J Virol 82:5307-15
Yi, Chae-Ryun; Rosenberg, Naomi (2007) Gag influences transformation by Abelson murine leukemia virus and suppresses nuclear localization of the v-Abl protein. J Virol 81:9461-8
Marchlik, Erica; Kalman, Richard; Rosenberg, Naomi (2005) Decreased virus population diversity in p53-null mice infected with weakly oncogenic Abelson virus. J Virol 79:11618-26
Kharas, Michael G; Deane, Jonathan A; Wong, Stephane et al. (2004) Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells. Blood 103:4268-75
Warren, David; Griffin, Deborah S; Mainville, Celine et al. (2003) The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus. J Virol 77:4617-25
Unnikrishnan, Indira; Rosenberg, Naomi (2003) Absence of p53 complements defects in Abelson murine leukemia virus signaling. J Virol 77:6208-15
Afar, D E; Han, L; McLaughlin, J et al. (1997) Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1. Immunity 6:773-82
Parmar, K; Rosenberg, N (1996) Ras complements the carboxyl terminus of v-Abl protein in lymphoid transformation. J Virol 70:1009-15
Raffel, G D; Parmar, K; Rosenberg, N (1996) In vivo association of v-Abl with Shc mediated by a non-phosphotyrosine-dependent SH2 interaction. J Biol Chem 271:4640-5
Wang, L C; Chen, Y Y; Rosenberg, N (1995) Pre-B-cells transformed by ts Abelson virus rearrange kappa and lambda [correction of gamma] genes in early G1. Curr Top Microbiol Immunol 194:355-61

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