Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA025462-16
Application #
2087378
Study Section
Experimental Virology Study Section (EVR)
Project Start
1979-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Genetics
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Chan, S Y; Ostrow, R S; Faras, A J et al. (1997) Genital papillomaviruses (PVs) and epidermodysplasia verruciformis PVs occur in the same monkey species: implications for PV evolution. Virology 228:213-7
Chan, S Y; Bernard, H U; Ratterree, M et al. (1997) Genomic diversity and evolution of papillomaviruses in rhesus monkeys. J Virol 71:4938-43
Liu, Z; Ghai, J; Ostrow, R S et al. (1995) The expression levels of the human papillomavirus type 16 E7 correlate with its transforming potential. Virology 207:260-70
Liu, Z; Ghai, J; Ostrow, R S et al. (1994) The E6 gene of human papillomavirus type 16 is sufficient for transformation of baby rat kidney cells in cotransfection with activated Ha-ras. Virology 201:388-96
Ostrow, R S; Liu, Z; Schneider, J F et al. (1993) The products of the E5, E6, or E7 open reading frames of RhPV 1 can individually transform NIH 3T3 cells or in cotransfections with activated ras can transform primary rodent epithelial cells. Virology 196:861-7
McGlennen, R C; Ghai, J; Ostrow, R S et al. (1992) Cellular transformation by a unique isolate of human papillomavirus type 11. Cancer Res 52:5872-8
Schneider, J F; McGlennen, R C; LaBresh, K V et al. (1991) Rhesus papillomavirus type 1 cooperates with activated ras in transforming primary epithelial rat cells independent of dexamethasone. J Virol 65:3354-8
Ostrow, R S; LaBresh, K V; Faras, A J (1991) Characterization of the complete RhPV 1 genomic sequence and an integration locus from a metastatic tumor. Virology 181:424-9
McGlennen, R C; Ostrow, R S; Carson, L F et al. (1991) Expression of cytokine receptors and markers of differentiation in human papillomavirus-infected cervical tissues. Am J Obstet Gynecol 165:696-705
Ostrow, R S; McGlennen, R C; Shaver, M K et al. (1990) A rhesus monkey model for sexual transmission of a papillomavirus isolated from a squamous cell carcinoma. Proc Natl Acad Sci U S A 87:8170-4

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