Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA026391-10
Application #
3167302
Study Section
Biochemistry Study Section (BIO)
Project Start
1979-07-01
Project End
1990-07-31
Budget Start
1990-05-01
Budget End
1990-07-31
Support Year
10
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Medin, J A; Gathy, K; Coleman, M S (1995) Expression of foreign proteins in Trichoplusia ni larvae. Methods Mol Biol 39:265-75
Yang, B; Gathy, K N; Coleman, M S (1994) Mutational analysis of residues in the nucleotide binding domain of human terminal deoxynucleotidyl transferase. J Biol Chem 269:11859-68
Bhaumik, D; Medin, J; Gathy, K et al. (1993) Mutational analysis of active site residues of human adenosine deaminase. J Biol Chem 268:5464-70
Medin, J A; Coleman, M S (1992) Lack of functional significance of Cys227 and Cys234 in terminal deoxynucleotidyltransferase. J Biol Chem 267:5199-201
Farrar, Y J; Evans, R K; Beach, C M et al. (1991) Interactions of photoactive DNAs with terminal deoxynucleotidyl transferase: identification of peptides in the DNA binding domain. Biochemistry 30:3075-82
Medin, J A; Hunt, L; Gathy, K et al. (1990) Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae. Proc Natl Acad Sci U S A 87:2760-4
Evans, R K; Coleman, M S (1989) Photoaffinity labeling of terminal deoxynucleotidyl transferase. 1. Active site directed interactions with 8-azido-2'-deoxyadenosine 5'-triphosphate. Biochemistry 28:707-12
Evans, R K; Beach, C M; Coleman, M S (1989) Photoaffinity labeling of terminal deoxynucleotidyl transferase. 2. Identification of peptides in the nucleotide binding domain. Biochemistry 28:713-20
Philips, A V; Coleman, M S; Maskos, K et al. (1989) Time-resolved fluorescence spectroscopy of human adenosine deaminase: effects of enzyme inhibitors on protein conformation. Biochemistry 28:2040-50
Robbins, D J; Coleman, M S (1988) Initiator role of double stranded DNA in terminal transferase catalyzed polymerization reactions. Nucleic Acids Res 16:2943-57

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