Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA028711-14
Application #
2087771
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1981-07-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
14
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Organized Research Units
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Sargent, R G; Meservy, J L; Perkins, B D et al. (2000) Role of the nucleotide excision repair gene ERCC1 in formation of recombination-dependent rearrangements in mammalian cells. Nucleic Acids Res 28:3771-8
Adair, G M; Rolig, R L; Moore-Faver, D et al. (2000) Role of ERCC1 in removal of long non-homologous tails during targeted homologous recombination. EMBO J 19:5552-61
Adair, G M; Scheerer, J B; Brotherman, A et al. (1998) Targeted recombination at the Chinese hamster APRT locus using insertion versus replacement vectors. Somat Cell Mol Genet 24:91-105
Limoli, C L; Kaplan, M I; Phillips, J W et al. (1997) Differential induction of chromosomal instability by DNA strand-breaking agents. Cancer Res 57:4048-56
Smith, D G; Adair, G M (1996) Characterization of an apparent hotspot for spontaneous mutation in exon 5 of the Chinese hamster APRT gene. Mutat Res 352:87-96
Scheerer, J B; Adair, G M (1994) Homology dependence of targeted recombination at the Chinese hamster APRT locus. Mol Cell Biol 14:6663-73
Nairn, R S; Adair, G M; Porter, T et al. (1993) Targeting vector configuration and method of gene transfer influence targeted correction of the APRT gene in Chinese hamster ovary cells. Somat Cell Mol Genet 19:363-75
Nairn, R S; Adair, G M; Christmann, C B et al. (1991) Ultraviolet stimulation of intermolecular homologous recombination in Chinese hamster ovary cells. Mol Carcinog 4:519-26
Walter, C A; Humphrey, R M; Adair, G M et al. (1991) Characterization of Chinese hamster ovary cells stably transformed by a plasmid with an inducible APRT gene. Plasmid 25:208-16
Adair, G M; Nairn, R S; Wilson, J H et al. (1990) Targeted gene replacement at the endogenous APRT locus in CHO cells. Somat Cell Mol Genet 16:437-41

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