Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA029133-11S1
Application #
3168558
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1981-08-01
Project End
1996-07-31
Budget Start
1993-08-01
Budget End
1994-07-31
Support Year
11
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20817
Shou, M; Yang, S K (1996) 3-Hydroxymethylcholanthrene: metabolic formation from 3-methylcholanthrene and stereoselective metabolism by rat liver microsomes. Drug Metab Dispos 24:595-601
Lu, X L; Guengerich, F P; Yang, S K (1991) Stereoselective metabolism of prazepam and halazepam by human liver microsomes. Drug Metab Dispos 19:637-42
Liu, K; Guengerich, F P; Yang, S K (1991) Enantioselective hydrolysis of lorazepam 3-acetate by esterases in human and rat liver microsomes and rat brain S9 fraction. Drug Metab Dispos 19:609-13
Shou, M G; Yang, S K (1990) Metabolism of 2S-hydroxy-3-methylcholanthrene by rat liver microsomes. Carcinogenesis 11:2037-45
Shou, M G; Yang, S K (1990) Enantioselective aliphatic hydroxylations of racemic 1-hydroxy-3-methylcholanthrene by rat liver microsomes. Chirality 2:141-9
Yang, S K; Mushtaq, M; Fu, P P (1990) Absolute configuration of cis-5,6-dihydrodiol enantiomers derived from helical conformers of 1,12-dimethylbenz[a]anthracene. Chirality 2:58-64
Shou, M; Yang, S K (1990) 9,10-Dihydroxy-9,10-dihydro-3-methylcholanthrene-2-one: a principal metabolite of the potent carcinogen 3-methylcholanthrene-2-one by rat liver microsomes. Carcinogenesis 11:689-95
Weems, H B; Yang, S K (1990) Resolution of enantiomeric triols, triol-hydroxyethylthioethers, and methoxy-triols derived from three benzo[a]pyrene diol-epoxides by chiral stationary phase high-performance liquid chromatography. J Chromatogr 535:239-53
Yang, S K; Prasanna, P; Weems, H B et al. (1990) Metabolism of the potent carcinogen 3-methylcholanthrylene by rat liver microsomes. Carcinogenesis 11:1195-201
Shou, M; Yang, S K (1990) 1-Hydroxy- and 2-hydroxy-3-methylcholanthrene: regioselective and stereoselective formations in the metabolism of 3-methylcholanthrene and enantioselective disposition in rat liver microsomes. Carcinogenesis 11:933-40

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