Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA031472-08S1
Application #
3169581
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1984-12-01
Project End
1994-03-31
Budget Start
1992-04-01
Budget End
1994-03-31
Support Year
8
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Keherly, M J; Hsieh, C C; McCombs, J L et al. (1996) Characterization of somatic cell hybrids exhibiting extinction of AFP, albumin and an AFP-HPRT transgene. Somat Cell Mol Genet 22:119-34
Rabek, J P; Zhang, D E; Torres-Ramos, C A et al. (1994) Analysis of the mechanism of glucocorticoid-mediated down regulation of the mouse alpha-fetoprotein gene. Biochim Biophys Acta 1218:136-44
Keherly, M J; Papaconstantinou, J; McCombs, J L (1993) A sequential staining technique for karyotypic analysis of interspecific somatic cell hybrids. Exp Cell Res 205:361-4
Beauchamp, R D; Sheng, H M; Alam, T et al. (1992) Posttranscriptional regulation of albumin and alpha-fetoprotein messenger RNA by transforming growth factor-beta 1 requires de novo RNA and protein synthesis. Mol Endocrinol 6:1789-96
Rabek, J P; Hsie, D Y; Papaconstantinou, J (1992) Alpha-fetoprotein expression in fetal kidney cells does not require enhancers. Biochim Biophys Acta 1130:317-25
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Zhang, D E; Hoyt, P R; Papaconstantinou, J (1990) Localization of DNA protein-binding sites in the proximal and distal promoter regions of the mouse alpha-fetoprotein gene. J Biol Chem 265:3382-91
Izban, M G; Papaconstantinou, J (1989) Cell-specific expression of mouse albumin promoter. Evidence for cell-specific DNA elements within the proximal promoter region and cis-acting DNA elements upstream of -160. J Biol Chem 264:9171-9
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