Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA033021-03S1
Application #
3170936
Study Section
Molecular Biology Study Section (MBY)
Project Start
1982-12-15
Project End
1986-01-31
Budget Start
1985-01-01
Budget End
1986-01-31
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
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Perucho, M; Welsh, J; Peinado, M A et al. (1995) Fingerprinting of DNA and RNA by arbitrarily primed polymerase chain reaction: applications in cancer research. Methods Enzymol 254:275-90
Perucho, M; Peinado, M A; Ionov, Y et al. (1994) Defects in replication fidelity of simple repeated sequences reveal a new mutator mechanism for oncogenesis. Cold Spring Harb Symp Quant Biol 59:339-48
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Shibata, D; Peinado, M A; Ionov, Y et al. (1994) Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat Genet 6:273-81
Shibata, D; Schaeffer, J; Li, Z H et al. (1993) Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J Natl Cancer Inst 85:1058-63
Peinado, M A; Malkhosyan, S; Velazquez, A et al. (1992) Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction. Proc Natl Acad Sci U S A 89:10065-9
Lopez-Galindez, C; Rojas, J M; Najera, R et al. (1991) Characterization of genetic variation and 3'-azido-3'-deoxythymidine- resistance mutations of human immunodeficiency virus by the RNase A mismatch cleavage method. Proc Natl Acad Sci U S A 88:4280-4
Jordano, J; Perucho, M (1988) Initial characterization of a potential transcriptional enhancer for the human c-K-ras gene. Oncogene 2:359-66
Yamamoto, F; Perucho, M (1988) Characterization of the human c-K-ras gene promoter. Oncogene Res 3:125-30

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