Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA034734-10S1
Application #
3172517
Study Section
Experimental Virology Study Section (EVR)
Project Start
1983-06-01
Project End
1994-11-30
Budget Start
1992-12-01
Budget End
1993-11-30
Support Year
10
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Ainsworth, J R; Rossi, L M; Murphy Jr, E C (1996) The Moloney murine sarcoma virus ts110 5' splice site signal contributes to the regulation of splicing efficiency and thermosensitivity. J Virol 70:6474-8
Touchman, J W; D'Souza, I; Heckman, C A et al. (1995) Branchpoint and polypyrimidine tract mutations mediating the loss and partial recovery of the Moloney murine sarcoma virus MuSVts110 thermosensitive splicing phenotype. J Virol 69:7724-33
Sterner, D A; Murphy Jr, E C (1992) Regulation of the efficiency and thermodependence of murine sarcoma virus MuSVts110 RNA splicing by sequences in both exons. Virology 191:638-48
Huai, L; Chiocca, S M; Gilbreth, M A et al. (1992) Moloney murine sarcoma virus MuSVts110 DNA: cloning, nucleotide sequence, and gene expression. J Virol 66:5329-37
Owen-Schaub, L B; de Mars, M; Murphy Jr, E C et al. (1991) IL-2 dose regulates TNF-alpha mRNA transcription and protein secretion in human peripheral blood lymphocytes. Cell Immunol 132:193-200
Chiocca, S M; Sterner, D A; Biggart, N W et al. (1991) Nickel mutagenesis: alteration of the MuSVts110 thermosensitive splicing phenotype by a nickel-induced duplication of the 3' splice site. Mol Carcinog 4:61-71
de Mars, M; Cizdziel, P E; Murphy Jr, E C (1990) Activation of cryptic splice sites in murine sarcoma virus-124 mutants. J Virol 64:5260-9
De Mars, M; Sterner, D A; Chiocca, S M et al. (1990) Regulation of RNA splicing in gag-deficient mutants of Moloney murine sarcoma virus MuSVts110. J Virol 64:1421-8
Owen-Schaub, L B; De Mars, M; Murphy Jr, E C et al. (1990) TNF-beta (lymphotoxin) strongly upregulates TNF-alpha gene expression in human peripheral blood lymphocytes. Lymphokine Res 9:491-7
Biggart, N W; Murphy Jr, E C (1988) Analysis of metal-induced mutations altering the expression or structure of a retroviral gene in a mammalian cell line. Mutat Res 198:115-29

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