Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA035541-12
Application #
2088994
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1987-09-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Chicago
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Chao, T S; Abe, M; Hershenson, M B et al. (1997) Src tyrosine kinase mediates stimulation of Raf-1 and mitogen-activated protein kinase by the tumor promoter thapsigargin. Cancer Res 57:3168-73
Xiong, W; Pestell, R G; Watanabe, G et al. (1997) Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. Am J Physiol 272:L1205-10
Morrison, P; Saltiel, A R; Rosner, M R (1996) Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C. J Biol Chem 271:12891-6
Morrison, P; Chung, K C; Rosner, M R (1996) Mutation of Di-leucine residues in the juxtamembrane region alters EGF receptor expression. Biochemistry 35:14618-24
Kuo, W L; Abe, M; Rhee, J et al. (1996) Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Mol Cell Biol 16:1458-70
Kelleher, M D; Abe, M K; Chao, T S et al. (1995) Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. Am J Physiol 268:L894-901
Hershenson, M B; Chao, T S; Abe, M K et al. (1995) Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells. J Biol Chem 270:19908-13
Englert, C; Hou, X; Maheswaran, S et al. (1995) WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. EMBO J 14:4662-75
Chao, T S; Foster, D A; Rapp, U R et al. (1994) Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium. J Biol Chem 269:7337-41
Hou, X; Johnson, A C; Rosner, M R (1994) Identification of an epidermal growth factor receptor transcriptional repressor. J Biol Chem 269:4307-12

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