Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA037435-12A2
Application #
2089377
Study Section
Radiation Study Section (RAD)
Project Start
1983-09-30
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Chicago
Department
Type
Organized Research Units
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Murley, Jeffrey S; Kataoka, Yasushi; Weydert, Christine J et al. (2006) Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065. Free Radic Biol Med 40:1004-16
Murley, Jeffrey S; Kataoka, Yasushi; Cao, Dingcai et al. (2004) Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res 162:536-46
Khodarev, Nikolai N; Kataoka, Yasushi; Murley, Jeffrey S et al. (2004) Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC). Int J Radiat Oncol Biol Phys 60:553-63
Elas, Martyna; Parasca, Adrian; Grdina, David J et al. (2003) Oral administration is as effective as intraperitoneal administration of amifostine in decreasing nitroxide EPR signal decay in vivo. Biochim Biophys Acta 1637:151-5
Grdina, David J; Kataoka, Yasushi; Murley, Jeffrey S et al. (2002) Antimetastatic effectiveness of amifostine therapy following surgical removal of Sa-NH tumors in mice. Semin Oncol 29:22-8
Grdina, David J; Murley, Jeffrey S; Kataoka, Yasushi et al. (2002) Differential activation of nuclear transcription factor kappaB, gene expression, and proteins by amifostine's free thiol in human microvascular endothelial and glioma cells. Semin Radiat Oncol 12:103-11
Grdina, David J; Kataoka, Yasushi; Murley, Jeffrey S et al. (2002) Inhibition of spontaneous metastases formation by amifostine. Int J Cancer 97:135-41
Khodarev, N N; Yu, J; Nodzenski, E et al. (2002) Method of RNA purification from endothelial cells for DNA array experiments. Biotechniques 32:316, 318, 320
Grdina, David J; Murley, Jeffrey S; Kataoka, Yasushi et al. (2002) Relationships between cytoprotection and mutation prevention by WR-1065. Mil Med 167:51-3
Murley, Jeffrey S; Kataoka, Yasushi; Weydert, Christine J et al. (2002) Delayed cytoprotection after enhancement of Sod2 (MnSOD) gene expression in SA-NH mouse sarcoma cells exposed to WR-1065, the active metabolite of amifostine. Radiat Res 158:101-9

Showing the most recent 10 out of 72 publications