Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA038942-11
Application #
2089680
Study Section
Experimental Immunology Study Section (EI)
Project Start
1984-05-11
Project End
1998-06-30
Budget Start
1996-08-20
Budget End
1998-06-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nevada Reno
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
146515460
City
Reno
State
NV
Country
United States
Zip Code
89557
Alves, Bryce N; Marshall, Kristen; Tamang, David L et al. (2009) Lipid-dependent cytotoxicity by the lipase PLRP2 and by PLRP2-positive cytotoxic T lymphocytes (CTLs). Cell Biochem Funct 27:296-308
Tamang, David L; Alves, Bryce N; Elliott, Viki et al. (2009) Regulation of perforin lysis: implications for protein disulfide isomerase proteins. Cell Immunol 255:82-92
Alves, Bryce; Leong, Jeff; Tamang, David L et al. (2009) Hydrolysis of tumor cell lipids after CTL-mediated death. Int Immunol 21:543-53
Alves, Bryce N; Leong, Jeff; Tamang, David L et al. (2009) Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity. J Leukoc Biol 86:701-12
Tamang, David L; Alves, Bryce N; Elliott, Viki et al. (2008) Low dose IL-15 induces snap arming of CD44(low) T lymphocytes in the absence of antigen. Cell Immunol 251:93-101
Tamang, David L; Redelman, Doug; Alves, Bryce N et al. (2006) Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal. Cytokine 36:148-59
Woolard, Matthew D; Hudig, Dorothy; Tabor, Leslie et al. (2005) NK cells in gamma-interferon-deficient mice suppress lung innate immunity against Mycoplasma spp. Infect Immun 73:6742-51
Kam, Chih-Min; Gotz, Marion G; Koot, Gretchen et al. (2004) Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C). Arch Biochem Biophys 427:123-34
Barao, Isabel; Hudig, Dorothy; Ascensao, Joao L (2003) IL-15-mediated induction of LFA-1 is a late step required for cytotoxic differentiation of human NK cells from CD34+Lin- bone marrow cells. J Immunol 171:683-90
Tran, Tinh V; Ellis, Karen A; Kam, Chih Min et al. (2002) Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity. Arch Biochem Biophys 403:160-70

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