Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA038951-03
Application #
3177478
Study Section
Immunobiology Study Section (IMB)
Project Start
1985-01-01
Project End
1987-07-31
Budget Start
1987-01-01
Budget End
1987-07-31
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Meeker, N D; Hickey, W F; Korngold, R et al. (1995) Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis. Proc Natl Acad Sci U S A 92:5684-8
Berger, M; Wettstein, P J; Korngold, R (1994) T cell subsets involved in lethal graft-versus-host disease directed to immunodominant minor histocompatibility antigens. Transplantation 57:1095-102
Murphy, G F; Sueki, H; Teuscher, C et al. (1994) Role of mast cells in early epithelial target cell injury in experimental acute graft-versus-host disease. J Invest Dermatol 102:451-61
Hill, L L; Perussia, B; McCue, P A et al. (1994) Effect of human natural killer cells on the metastatic growth of human melanoma xenografts in mice with severe combined immunodeficiency. Cancer Res 54:763-70
Korngold, R; Leighton, C; Manser, T (1994) Graft-versus-myeloid leukemia responses following syngeneic and allogeneic bone marrow transplantation. Transplantation 58:278-87
Korngold, R (1993) Biology of graft-vs.-host disease. Am J Pediatr Hematol Oncol 15:18-27
Shanley, J D; Korngold, R; Forman, S J (1993) The effect of graft-versus-host disease in response to minor histocompatibility antigens on acute murine cytomegalovirus infection. Transplantation 56:487-9
Korngold, R (1992) Lethal graft-versus-host disease in mice directed to multiple minor histocompatibility antigens: features of CD8+ and CD4+ T cell responses. Bone Marrow Transplant 9:355-64
Wettstein, P J; Korngold, R (1992) T cell subsets required for in vivo and in vitro responses to single and multiple minor histocompatibility antigens. Transplantation 54:296-307
Murphy, G F; Whitaker, D; Sprent, J et al. (1991) Characterization of target injury of murine acute graft-versus-host disease directed to multiple minor histocompatibility antigens elicited by either CD4+ or CD8+ effector cells. Am J Pathol 138:983-90

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