Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA039064-13
Application #
2089717
Study Section
Pathology A Study Section (PTHA)
Project Start
1984-07-01
Project End
2000-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Kindzelskii, Andrei L; Amhad, Imran; Keller, Donald et al. (2004) Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinase-type plasminogen activator. Histochem Cell Biol 121:299-310
Worth, R G; Esper, R M; Warra, N S et al. (2001) Mercury inhibition of neutrophil activity: evidence of aberrant cellular signalling and incoherent cellular metabolism. Scand J Immunol 53:49-55
Mahdi, F; Shariat-Madar, Z; Todd 3rd, R F et al. (2001) Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells. Blood 97:2342-50
Kindzelskii, A L; Yang, Z; Nabel, G J et al. (2000) Ebola virus secretory glycoprotein (sGP) diminishes Fc gamma RIIIB-to-CR3 proximity on neutrophils. J Immunol 164:953-8
Shaya, S; Kindzelskii, A L; Minor, J et al. (1998) Aberrant integrin (CR4;alpha(x)beta2;CD11c/CD18) oscillations on neutrophils in a mild form of pyoderma gangrenosum. J Invest Dermatol 111:154-8
Mizukami, I F; Todd 3rd, R F (1998) A soluble form of the urokinase plasminogen activator receptor (suPAR) can bind to hematopoietic cells. J Leukoc Biol 64:203-13
Sitrin, R G; Pan, P M; Srikanth, S et al. (1998) Fibrinogen activates NF-kappa B transcription factors in mononuclear phagocytes. J Immunol 161:1462-70
Model, M A; Ganelina, L S; Todd 3rd, R F (1998) A microscopic study of Fc gamma RIII-mediated respiratory burst in neutrophils. Immunobiology 199:39-50
Adachi, Y; Kindzelskii, A L; Cookingham, G et al. (1998) Aberrant neutrophil trafficking and metabolic oscillations in severe pyoderma gangrenosum. J Invest Dermatol 111:259-68
Xue, W; Mizukami, I; Todd 3rd, R F et al. (1997) Urokinase-type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: dependence on extracellular matrix components. Cancer Res 57:1682-9

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