Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA039582-11
Application #
2089877
Study Section
Radiation Study Section (RAD)
Project Start
1985-04-01
Project End
1997-06-30
Budget Start
1995-04-01
Budget End
1997-06-30
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
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Prise, K M; Gillies, N E; Whelan, A et al. (1995) Role of charge in the radioprotection of E. coli by thiols. Int J Radiat Biol 67:393-401
Milligan, J R; Ng, J Y; Wu, C C et al. (1995) DNA repair by thiols in air shows two radicals make a double-strand break. Radiat Res 143:273-80
Zheng, S; Newton, G L; Ward, J F et al. (1992) Aerobic radioprotection of pBR322 by thiols: effect of thiol net charge upon scavenging of hydroxyl radicals and repair of DNA radicals. Radiat Res 130:183-93
Aguilera, J A; Newton, G L; Fahey, R C et al. (1992) Thiol uptake by Chinese hamster V79 cells and aerobic radioprotection as a function of the net charge on the thiol. Radiat Res 130:194-204
Fahey, R C; Vojnovic, B; Michael, B D (1991) The effects of counter-ion condensation and co-ion depletion upon the rates of chemical repair of poly(U) radicals by thiols. Int J Radiat Biol 59:885-99
Fahey, R C; Prise, K M; Stratford, M R et al. (1991) Rates for repair of pBR 322 DNA radicals by thiols as measured by the gas explosion technique: evidence that counter-ion condensation and co-ion depletion are significant at physiological ionic strength. Int J Radiat Biol 59:901-17
Fahey, R C; Sundquist, A R (1991) Evolution of glutathione metabolism. Adv Enzymol Relat Areas Mol Biol 64:1-53
Loh, S N; Dethlefsen, L A; Newton, G L et al. (1990) Nuclear thiols: technical limitations on the determination of endogenous nuclear glutathione and the potential importance of sulfhydryl proteins. Radiat Res 121:98-106
Ward, J F (1988) DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog Nucleic Acid Res Mol Biol 35:95-125

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