Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA039621-03
Application #
3178826
Study Section
Experimental Immunology Study Section (EI)
Project Start
1985-04-01
Project End
1988-03-31
Budget Start
1987-05-01
Budget End
1988-03-31
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Datta, Shyamasree; Barrera, Natilibeth; Pavicic Jr, Paul G et al. (2015) cEBP Homologous Protein Expression in Macrophages Regulates the Magnitude and Duration of IL-6 Expression and Dextran Sodium Sulfate Colitis. J Interferon Cytokine Res 35:785-94
Bhatt, Sumantha; Qin, Jie; Bennett, Carole et al. (2014) All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function. J Immunol 192:5098-108
Zhao, Chenyang; Pavicic Jr, Paul G; Datta, Shyamasree et al. (2014) Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1. J Immunol 193:879-88
Herjan, Tomasz; Novotny, Michael; Hamilton, Thomas A (2013) Diversity in sequence-dependent control of GRO chemokine mRNA half-life. J Leukoc Biol 93:895-904
Hamilton, Thomas; Li, Xiaoxia; Novotny, Michael et al. (2012) Cell type- and stimulus-specific mechanisms for post-transcriptional control of neutrophil chemokine gene expression. J Leukoc Biol 91:377-83
Bulek, Katarzyna; Liu, Caini; Swaidani, Shadi et al. (2011) The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation. Nat Immunol 12:844-52
Sun, Dongxu; Novotny, Michael; Bulek, Katarzyna et al. (2011) Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF). Nat Immunol 12:853-60
Hamilton, Thomas; Novotny, Michael; Pavicic Jr, Paul J et al. (2010) Diversity in post-transcriptional control of neutrophil chemoattractant cytokine gene expression. Cytokine 52:116-22
Datta, Shyamasree; Novotny, Michael; Pavicic Jr, Paul G et al. (2010) IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence. J Immunol 184:1484-91
Hartupee, Justin; Liu, Caini; Novotny, Michael et al. (2009) IL-17 signaling for mRNA stabilization does not require TNF receptor-associated factor 6. J Immunol 182:1660-6

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