Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA040489-04S1
Application #
3180524
Study Section
Pathology B Study Section (PTHB)
Project Start
1985-07-01
Project End
1990-05-31
Budget Start
1988-06-01
Budget End
1989-05-31
Support Year
4
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92037
Wieland, Stefan F (2015) The chimpanzee model for hepatitis B virus infection. Cold Spring Harb Perspect Med 5:
Guidotti, Luca G; Isogawa, Masanori; Chisari, Francis V (2015) Host-virus interactions in hepatitis B virus infection. Curr Opin Immunol 36:61-6
Sitia, Giovanni; Iannacone, Matteo; Aiolfi, Roberto et al. (2011) Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. PLoS Pathog 7:e1002061
Bissig, Karl-Dimiter; Wieland, Stefan F; Tran, Phu et al. (2010) Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. J Clin Invest 120:924-30
Chisari, F V; Isogawa, M; Wieland, S F (2010) Pathogenesis of hepatitis B virus infection. Pathol Biol (Paris) 58:258-66
Yang, Priscilla L; Althage, Alana; Chung, Josan et al. (2010) Immune effectors required for hepatitis B virus clearance. Proc Natl Acad Sci U S A 107:798-802
Bandi, Prasanthi; Garcia, Mayra L; Booth, Carmen J et al. (2010) Bortezomib inhibits hepatitis B virus replication in transgenic mice. Antimicrob Agents Chemother 54:749-56
Iannacone, Matteo; Sitia, Giovanni; Isogawa, Masanori et al. (2008) Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus. Proc Natl Acad Sci U S A 105:629-34
Maier, Holly; Isogawa, Masanori; Freeman, Gordon J et al. (2007) PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. J Immunol 178:2714-20
Robek, Michael D; Garcia, Mayra L; Boyd, Bryan S et al. (2007) Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. J Virol 81:483-91

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