Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA041261-12
Application #
2090403
Study Section
Radiation Study Section (RAD)
Project Start
1985-12-01
Project End
2001-01-31
Budget Start
1996-05-31
Budget End
1997-01-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
Organized Research Units
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Ribar, Balazs; Prakash, Louise; Prakash, Satya (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27:3211-6
Ribar, Balazs; Prakash, Louise; Prakash, Satya (2006) Requirement of ELC1 for RNA polymerase II polyubiquitylation and degradation in response to DNA damage in Saccharomyces cerevisiae. Mol Cell Biol 26:3999-4005
Guzder, Sami N; Sommers, Christopher H; Prakash, Louise et al. (2006) Complex formation with damage recognition protein Rad14 is essential for Saccharomyces cerevisiae Rad1-Rad10 nuclease to perform its function in nucleotide excision repair in vivo. Mol Cell Biol 26:1135-41
Guzder, Sami N; Torres-Ramos, Carlos; Johnson, Robert E et al. (2004) Requirement of yeast Rad1-Rad10 nuclease for the removal of 3'-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev 18:2283-91
Yu, Sung-Lim; Lee, Sung-Keun; Johnson, Robert E et al. (2003) The stalling of transcription at abasic sites is highly mutagenic. Mol Cell Biol 23:382-8
Johnson, Robert E; Yu, Sung-Lim; Prakash, Satya et al. (2003) Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Genes Dev 17:77-87
Lee, Sung-Keun; Yu, Sung-Lim; Prakash, Louise et al. (2002) Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome. Cell 109:823-34
Lee, Sung-Keun; Yu, Sung-Lim; Prakash, Louise et al. (2002) Yeast RAD26, a homolog of the human CSB gene, functions independently of nucleotide excision repair and base excision repair in promoting transcription through damaged bases. Mol Cell Biol 22:4383-9
Unk, Ildiko; Haracska, Lajos; Gomes, Xavier V et al. (2002) Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen. Mol Cell Biol 22:6480-6
Unk, I; Haracska, L; Prakash, S et al. (2001) 3'-phosphodiesterase and 3'-->5' exonuclease activities of yeast Apn2 protein and requirement of these activities for repair of oxidative DNA damage. Mol Cell Biol 21:1656-61

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