Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA042971-11
Application #
2091040
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1989-08-03
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Pathology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Stankunas, Kryn; Shang, Ching; Twu, Karen Y et al. (2008) Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. Circ Res 103:702-9
Chang, Ching-Pin; Stankunas, Kryn; Shang, Ching et al. (2008) Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract. Development 135:3577-86
Ficara, Francesca; Murphy, Mark J; Lin, Min et al. (2008) Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence. Cell Stem Cell 2:484-96
Wong, Piu; Iwasaki, Masayuki; Somervaille, Tim C P et al. (2007) Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential. Genes Dev 21:2762-74
Sanyal, Mrinmoy; Tung, James W; Karsunky, Holger et al. (2007) B-cell development fails in the absence of the Pbx1 proto-oncogene. Blood 109:4191-9
Brendolan, Andrea; Ferretti, Elisabetta; Salsi, Valentina et al. (2005) A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny. Development 132:3113-26
Selleri, Licia; DiMartino, Jorge; van Deursen, Jan et al. (2004) The TALE homeodomain protein Pbx2 is not essential for development and long-term survival. Mol Cell Biol 24:5324-31
Manley, Nancy R; Selleri, Licia; Brendolan, Andrea et al. (2004) Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol 276:301-12
Rhee, Joon Whan; Arata, Akiko; Selleri, Licia et al. (2004) Pbx3 deficiency results in central hypoventilation. Am J Pathol 165:1343-50
Smith, Kevin S; Chanda, Sumit K; Lingbeek, Merel et al. (2003) Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol Cell 12:393-400

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