Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA043322-12
Application #
2091172
Study Section
Radiation Study Section (RAD)
Project Start
1986-01-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Fabre, Kristin M; Ramaiah, Lila; Dregalla, Ryan C et al. (2011) Murine Prkdc polymorphisms impact DNA-PKcs function. Radiat Res 175:493-500
Williams, Eli S; Klingler, Rebekah; Ponnaiya, Brian et al. (2009) Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence. Cancer Res 69:2100-7
Carsten, Ronald E; Bachand, Annette M; Bailey, Susan M et al. (2008) Resveratrol reduces radiation-induced chromosome aberration frequencies in mouse bone marrow cells. Radiat Res 169:633-8
Hagelstrom, R T; Askin, K F; Williams, A J et al. (2008) DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals. Oncogene 27:6761-9
Williams, Eli S; Stap, Jan; Essers, Jeroen et al. (2007) DNA double-strand breaks are not sufficient to initiate recruitment of TRF2. Nat Genet 39:696-8;author reply 698-9
Bailey, Susan M; Murnane, John P (2006) Telomeres, chromosome instability and cancer. Nucleic Acids Res 34:2408-17
Bailey, S M; Goodwin, E H; Cornforth, M N (2004) Strand-specific fluorescence in situ hybridization: the CO-FISH family. Cytogenet Genome Res 107:14-7
Bailey, Susan M; Brenneman, Mark A; Halbrook, James et al. (2004) The kinase activity of DNA-PK is required to protect mammalian telomeres. DNA Repair (Amst) 3:225-33
Bailey, Susan M; Brenneman, Mark A; Goodwin, Edwin H (2004) Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells. Nucleic Acids Res 32:3743-51
Bailey, Susan M; Cornforth, Michael N; Ullrich, Robert L et al. (2004) Dysfunctional mammalian telomeres join with DNA double-strand breaks. DNA Repair (Amst) 3:349-57

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