Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA046838-08
Application #
2092332
Study Section
Radiation Study Section (RAD)
Project Start
1988-03-01
Project End
2000-02-29
Budget Start
1996-05-15
Budget End
1997-02-28
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Greene, Kellee F; Budzinski, Edwin E; Iijima, Herbert et al. (2007) Assessment of DNA damage at the dimer level: measurement of the formamide lesion. Radiat Res 167:146-51
Bailey, Douglas T; DeFedericis, Han-Chun C; Greene, Kellee F et al. (2006) A novel approach to DNA damage assessments: measurement of the thymine glycol lesion. Radiat Res 165:438-44
DeFedericis, Han-Chun; Patrzyc, Helen B; Rajecki, Michael J et al. (2006) Singlet oxygen-induced DNA damage. Radiat Res 165:445-51
Dawidzik, J B; Budzinski, E E; Patrzyc, H B et al. (2004) Dihydrothymine lesion in X-irradiated DNA: characterization at the molecular level and detection in cells. Int J Radiat Biol 80:355-61
Iijima, Herbert; Patrzyc, Helen B; Dawidzik, Jean B et al. (2004) Measurement of DNA adducts in cells exposed to cisplatin. Anal Biochem 333:65-71
Box, H C; Dawidzik, J B; Budzinski, E E (2001) Free radical-induced double lesions in DNA. Free Radic Biol Med 31:856-68
Box, H C; Budzinski, E E; Dawidzik, J et al. (2001) A novel double lesion in X-irradiated DNA consists of a strand break and a base modification. Radiat Res 156:215-9
Maccubbin, A E; Iijima, H; Ersing, N et al. (2000) Double-base lesions are produced in DNA by free radicals. Arch Biochem Biophys 375:119-23
Box, H C; Patrzyc, H B; Dawidzik, J B et al. (2000) Double base lesions in DNA X-irradiated in the presence or absence of oxygen. Radiat Res 153:442-6
Maccubbin, A E; Patrzyc, H B; Ersing, N et al. (1999) Assay for reactive oxygen species-induced DNA damage: measurement of the formamido and thymine glycol lesions. Biochim Biophys Acta 1454:80-8

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